Scientists have long believed the human immunodeficiency virus (HIV) could hide in surprising and hard-to-reach areas. New research shows HIV can hide in the bone marrow, avoiding drugs and complicating treatment.
Dr. Kathleen Collins of the University of Michigan and her colleagues report in this week's edition of the journal Nature Medicine that the HIV virus can infect long-lived bone marrow cells that eventually convert into blood cells. The virus is dormant in the bone marrow cells, she said, but when those progenitor cells develop into blood cells, it can be reactivated and cause renewed infection. The virus kills the new blood cells and then moves on to infect other cells, said. "If we're ever going to be able to find a way to get rid of the cells, the first step is to understand" where a latent infection can continue."
Scientists have also discovered HIV dormant in blood cells called macrophages and in memory T-cells. Finding these sources of infection are key because eliminating them would allow AIDS patients to stop taking expensive anti-retroviral drugs after their infection was over. That's critical in many countries where the treatment is hard to afford and deliver.








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Posted by: HouseOfNumbers | 09 March 2010 at 14:06
The more we know the more we dont know... therefore WE should take what we do know for certain more seriously. i.e the manner in which it is transmitted!
Far too many young men are still becoming infected today.
Posted by: nahtans | 09 March 2010 at 16:15
couldn't agree with you more nahtans. our community has been dealing with this now close to 30 years yet so few of us have modified our behavior. that's the sad part to me.
Posted by: FREELEO | 09 March 2010 at 16:47
@nahtans and FREELEO
Co-sign 100%.
Posted by: MW09 | 10 March 2010 at 16:37